Standard of care (androgen deprivation therapy alone or with intravenous docetaxel 75 mg/m2 once every 3 weeks, N:296), standard of care plus radiotherapy (N:293), standard of care plus abiraterone (N:292), or standard of care plus radiotherapy plus abiraterone (N:291)
Efficacy
Patients assigned to receive abiraterone (n=583) had longer radiographic PFS [HR:0·54, 0·41–0·71; p<0·0001] and OS [0·82, 0·69–0·98; p=0·030] than patients who did not receive abiraterone (n=589)
mOS: 5·72 years vs 4·72 years (abiraterone plus SOC vs SOC)
Safety
Grade >= 3 AEs : 63% vs 52% (abiraterone, ADT plus docetaxel vs ADT plus docetaxel), hypertencion (22% vs 13%)
